Liberty Books & News is a relatively new bookstore at The Shops on Lane Avenue (1649 West Lane Avenue) in Columbus, OH. If you are a reader, you seriously have to check this store out. It's got an excellent selection of both children's and grown-up's books, and it has the single best magazine section I've seen in town, hands-down. Not only do they carry Locus and the SFWA Journal, they have issues of The Journal of Irreproducible Results.
The comics section is much better than in most bookstores, but of course can't touch the offerings of the city's actual comic book shops, such as Midgard Comics (5541 Westerville Rd # 312g, Westerville, OH) or the Laughing Ogre (4258 N High St, Columbus, OH).
As added bonuses, Liberty Books & News has comfy chairs, free coffee, and offers author readings.
May 23, 2007 Update: Sadly, Liberty Books will be closing its doors soon.